- Dance Companies, South Portland
- Data Processing Services, South Portland
- Day Camps, South Portland
- Deaf Services, South Portland
- Deck Cleaning & Restoration, South Portland - Clean & Seal Decks, Patios, Fences, etc
- Deck, Patio & Gazebo Design, Building, Cleaning, Repair & Maintenance Contractors, South Portland
- Decorating & Designing Services, South Portland
- Dental Supplies & Equipment, South Portland
- Dentists, South Portland
- Dentures, South Portland
- Department Stores, South Portland
- Dermatologists, South Portland - Skin Doctors, Physicians & Surgeons (Dermatology)
- Designer Clothes & Accessories, South Portland
- Developmental Disabilities, South Portland
- Diabetes Doctors, South Portland - Endocrinologists Physicians & Surgeons
- Diesel, South Portland - Engine Fuels, Oils & Lubricants
- Diet Center, South Portland
- Diet Centers, South Portland
- Digital Printing & Imaging Service, South Portland
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- Diner Restaurants, South Portland
- Direct Mail Advertising Services, South Portland
- Disabled Persons Assistive Services, South Portland
- Disc Jockeys, South Portland
- Discount Stores, South Portland - Clothing, Grocery, Furniture, Etc
- Diving Instruction, South Portland
- Divorce & Family Law Attorneys & Lawyers, South Portland
- Doctorate Degree, South Portland
- Doctors, Physicians & Surgeons, South Portland
- Donuts, South Portland
- Doors & Door Frames, South Portland - Exterior, Interior, French, Front Entry, Patio, Storm, Garage & Sliding Glass Doors
- Drinking Establishments, South Portland
- Drugs, Pharmaceutical Products & Toiletries - Wholesale & Manufacturers, South Portland
- Dry Cleaning & Laundry, South Portland - Dry Cleaners
- Dryer Vent Cleaning, Repair & Installation, South Portland
- Drying Equipment Industrial, South Portland
- Drywall, Insulation & Plaster Contractors, South Portland - Installation & Repair Services
- Duct Work & Duct Supplies & Equipment, South Portland
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