- Sails, Southwest Harbor
- Sand Gravel & Aggregate, Southwest Harbor
- Sandwich Shop Restaurants, Southwest Harbor
- Septic Tank Installation & Repair, Southwest Harbor - Septic Systems
- Septic Tank Pumping & Cleaning, Southwest Harbor - Septic Systems
- Septic Tanks & Septic Systems Contractors, Southwest Harbor - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Septic Tanks & Systems, Southwest Harbor - Wholesale, Dealers & Suppliers
- Ship & Boat Building & Repairing, Southwest Harbor
- Shopping & Shopping Services, Southwest Harbor
- Signs, Southwest Harbor
- Social Clubs & Organizations, Southwest Harbor
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- Social Services & Welfare, Southwest Harbor
- Special Interest Schools Or Instruction, Southwest Harbor
- Specialty Stores, Southwest Harbor
- Specialty Vehicle Rental & Leasing, Southwest Harbor
- Sporting Goods Equipment Rental, Southwest Harbor
- Sporting Goods Manufacturers, Southwest Harbor
- Sporting Goods Stores, Southwest Harbor
- Sports Bars & Lounges, Southwest Harbor
- State Government, Southwest Harbor
- Substance Abuse Clinics, Southwest Harbor - Alcoholism, Addiction & Drug Abuse Treatment Centers
- Surveyor Services, Southwest Harbor - Surveying Service
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